Description

3-(2-Thienyl)-5-Isoxazolecarboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thienyl-isoxazole scaffold.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic & Institutional Research: Employed in university and government labs for fundamental research in heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	3-(2-Thienyl)-5-Isoxazolecarboxylic Acid
CAS No.	204910-49-6
Molecular Formula	C8H5NO3S
Molecular Weight	195.20 g/mol
Synonyms	5-Isoxazolecarboxylic acid, 3-(2-thienyl)-; 3-(Thiophen-2-yl)-1,2-oxazole-5-carboxylic acid; 3-(2-Thienyl)isoxazole-5-carboxylic acid; 2-Thienyl-5-isoxazolecarboxylic acid; Thienylisoxazolecarboxylic acid; TICA; CAS 204910-49-6
EINECS	Contact for details

Quality Control

Our 3-(2-Thienyl)-5-Isoxazolecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.