Description

(S)-Tetrahydrofuran-3-Amine Hydrochloride CAS NO 204512-95-8 is a high-purity chiral amine hydrochloride salt, a key building block in modern organic synthesis. Its value lies in its well-defined stereochemistry and stability, which are critical for producing enantiomerically pure compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into the backbone of peptide analogs to modulate biological activity and stability.
• Material Science: Employed in the synthesis of specialty polymers and functional materials requiring specific chiral centers.
• Chemical Biology Probes: Used to create labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	(S)-Tetrahydrofuran-3-Amine Hydrochloride
CAS No.	204512-95-8
Molecular Formula	C4H10ClNO
Molecular Weight	123.58 g/mol
Synonyms	(S)-3-Aminotetrahydrofuran Hydrochloride; (3S)-3-Aminotetrahydrofuran Hydrochloride; (S)-Tetrahydro-3-furanamine Hydrochloride; (S)-3-Furanamine, tetrahydro-, hydrochloride; (S)-Aminotetrahydrofuran HCl; (S)-THF-3-Amine HCl; (S)-3-Aminotetrahydrofuran HCl; (S)-3-Tetrahydrofuranylamine Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (S)-Tetrahydrofuran-3-Amine Hydrochloride is produced under strict quality management systems. We ensure compliance with ICH guidelines for impurities and utilize advanced analytical techniques like HPLC, GC, and chiral analysis to guarantee identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.