Description

(R)-2-Methylpyrrolidine Tosylate is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals, where the specific (R)-enantiomer is crucial for biological activity. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas like neurology and metabolic diseases.

Application

• As a key chiral intermediate in the synthesis of pharmaceutical candidates and approved drugs.
• For use in asymmetric catalysis and the preparation of chiral ligands or auxiliaries.
• In medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• As a building block for the development of agrochemicals and specialty fine chemicals.
• In process chemistry for the scale-up and commercial manufacturing of enantiomerically pure compounds.

Basic Information

Product Name	(R)-2-Methylpyrrolidine Tosylate
CAS No.	204387-55-3
Molecular Formula	C12H17NO3S
Molecular Weight	255.33 g/mol
Synonyms	(R)-2-Methylpyrrolidine p-Toluenesulfonate; (R)-N-Methylpyrrolidinium Tosylate; (R)-1-Methyl-2-pyrrolidinyl Tosylate; (R)-2-Methylpyrrolidinium p-Toluenesulfonate; (R)-α-Methylpyrrolidine Tosylate; (R)-2-Pyrrolidinemethanol, 1-methyl-, 1-(4-methylbenzenesulfonate); (R)-N-Methyl-2-pyrrolidinemethanol Tosylate
EINECS	Contact for details

Quality Control

Our (R)-2-Methylpyrrolidine Tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.