Description

8-Bromo-4-Chromanone is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core chromanone scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides due to its bioactive heterocyclic structure.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and host materials in the fabrication of OLED devices.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Flavor and Fragrance Chemistry: Utilized as an intermediate for synthesizing certain aroma chemicals and synthetic flavors.
• Academic and Contract Research: Essential for methodological studies in organic chemistry, including cross-coupling reactions and ring-forming transformations.

Basic Information

Product Name	8-Bromo-4-Chromanone
CAS No.	204377-88-8
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	8-Bromochroman-4-one; 4-Chromanone, 8-bromo-; 8-Bromo-3,4-dihydro-2H-1-benzopyran-4-one; 8-Bromo-4-chromone; 8-Bromodihydrocoumarin-4-one
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chromanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.