Description

8-Azabicyclo[3.2.1]Octan-3-Amine, 8-Methyl-, Hydrochloride (1:1) is a high-purity, nitrogen-containing bicyclic amine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chiral building block for constructing complex molecular architectures. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Chiral Building Block: Utilized in asymmetric synthesis to introduce the 8-azabicyclo[3.2.1]octane scaffold, a privileged structure in medicinal chemistry.
• Agrochemical Research: Serves as an intermediate in the development of new pesticides and herbicides with specific biological activity.
• Ligand Synthesis: Used for constructing complex ligands in catalysis and coordination chemistry.
• Academic & R&D: Employed in research laboratories for methodological studies and the exploration of new chemical entities.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals and performance materials.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octan-3-Amine, 8-Methyl-, Hydrochloride (1:1)
CAS No.	203664-57-7
Molecular Formula	C8H16N2 • HCl
Molecular Weight	176.69 g/mol (Free base: 140.23 g/mol)
Synonyms	8-Methyl-8-azabicyclo[3.2.1]octan-3-amine hydrochloride; Tropan-3-amine, 8-methyl-, hydrochloride (1:1); 3-Amino-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride; 8-Methyl-3-aminotropane HCl; Nortropine-3-amine, N-methyl-, hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octan-3-Amine, 8-Methyl-, Hydrochloride (1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are available upon request. We can support development and production needs across various purity grades, from research to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.