Description

7-Azaspiro[3.5]Nonane-2-Carbonitrile CAS NO 203662-67-3 is a high-value, nitrogen-containing spirocyclic building block and advanced pharmaceutical intermediate. This compound is prized for its unique rigid, three-dimensional structure, which is instrumental in modulating the physicochemical and biological properties of drug candidates. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of new therapeutic agents, particularly for central nervous system (CNS) disorders, oncology, and anti-infectives.
• Medicinal Chemistry Building Block: Used to introduce conformational restraint and improve metabolic stability, solubility, and target selectivity in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, spirocyclic architectures.
• Academic & Industrial R&D: Employed in research institutions and corporate R&D labs for exploring new chemical space and reaction methodologies.

Basic Information

Product Name	7-Azaspiro[3.5]Nonane-2-Carbonitrile
CAS No.	203662-67-3
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	7-Azaspiro[3.5]nonane-2-carbonitrile; 2-Cyano-7-azaspiro[3.5]nonane; 7-Azaspiro[3.5]nonane-2-carbonitrile; 2-Cyano-7-azaspiro[3.5]nonane; 7-Aza-spiro[3.5]nonane-2-carbonitrile; 7-Azaspiro[3.5]nonane-2-carbonitrile; 7-Azaspiro[3.5]nonane-2-carbonitrile (9CI); 7-Azaspiro[3.5]nonane-2-carbonitrile, 2-Cyano-7-azaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our 7-Azaspiro[3.5]Nonane-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.