Description

2-Amino-7-Fluoro-3-Methylquinoline is a high-purity, fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines an amino group with a fluorine substituent on the quinoline scaffold, enabling precise modifications in target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other functional organic materials due to its electron-donating and accepting properties.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Ligand and Catalyst Preparation: Utilized to develop novel ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	2-Amino-7-Fluoro-3-Methylquinoline
CAS No.	203506-29-0
Molecular Formula	C₁₀H₉FN₂
Molecular Weight	176.19 g/mol
Synonyms	7-Fluoro-3-methylquinolin-2-amine; 3-Methyl-7-fluoroquinolin-2-amine; 2-Amino-7-fluoro-3-methylquinoline; 203506-29-0; Quinoline, 2-amino-7-fluoro-3-methyl-; 7-Fluoro-2-amino-3-methylquinoline; 2-Amino-7-fluoro-3-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 2-Amino-7-Fluoro-3-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.