Description

(R)-2-Benzylpiperidine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its well-defined stereochemistry, which is critical for developing enantiomerically pure pharmaceuticals and bioactive compounds. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic and stoichiometric asymmetric reactions to construct complex molecules with high enantiomeric excess.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Development: Employed in the synthesis of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-2-Benzylpiperidine Hydrochloride
CAS No.	203452-46-4
Molecular Formula	C12H18ClN
Molecular Weight	211.73 g/mol
Synonyms	(R)-2-Benzylpiperidine HCl; (R)-2-Benzylpiperidine Hydrochloride; (R)-α-Benzylpiperidine Hydrochloride; (R)-2-(Phenylmethyl)piperidine Hydrochloride; (R)-N-Benzylpiperidine Hydrochloride; (2R)-2-Benzylpiperidine Hydrochloride; (R)-Benzylpiperidine HCl; Piperidine, 2-(phenylmethyl)-, (2R)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Benzylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.