Description

2(1H)-Quinolinone, 7-[4-[4-(3,4-Dichlorophenyl)-1-Piperazinyl]Butoxy]-3,4-Dihydro- is a high-purity, synthetic organic compound belonging to the quinolinone class, featuring a piperazine-substituted butoxy side chain. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel therapeutic agents, particularly in central nervous system (CNS) research. It is essential for R&D and manufacturing teams in the pharmaceutical, biotechnology, and academic research sectors requiring precise and reliable building blocks for drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for CNS-targeted therapies.
• Biochemical Research: Used as a reference standard or active compound in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead molecules.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and neuropharmacology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.
• Reference Material: Utilized for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	2(1H)-Quinolinone, 7-[4-[4-(3,4-Dichlorophenyl)-1-Piperazinyl]Butoxy]-3,4-Dihydro-
CAS No.	203395-75-9
Molecular Formula	C23H25Cl2N3O2
Molecular Weight	446.37 g/mol
Synonyms	7-[4-[4-(3,4-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; 7-[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydroquinolin-2(1H)-one; 203395-75-9; UNII-3K3R8T4Y1P; 3,4-Dihydro-7-[4-[4-(3,4-dichlorophenyl)-1-piperazinyl]butoxy]-2(1H)-quinolinone; A-77636 (hydrochloride salt form); A77636
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.