Description

cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Dec-3-En-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and azaspirodecenone structure. This compound is of significant value in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in synthetic organic chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Chemical Research & Development: Used as a versatile scaffold for exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Academic Research: Serves as a valuable reagent in university and institutional labs for studying spirocyclic compound synthesis and properties.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and complex organic molecules.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related API manufacturing.

Basic Information

Product Name	cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Dec-3-En-2-One
CAS No.	203312-38-3
Molecular Formula	C19H25NO3
Molecular Weight	315.41 g/mol
Synonyms	cis-3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one; 1-Azaspiro[4.5]dec-3-en-2-one, 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-, (3Z)-; (3Z)-3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one; 203312-38-3; cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Dec-3-En-2-One; Azaspirodecenone derivative; Spirocyclic lactam intermediate.
EINECS	Contact for details

Quality Control

Our cis-3-(2,5-Dimethylphenyl)-4-Hydroxy-8-Methoxy-1-Azaspiro[4.5]Dec-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with material produced under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.