Description

(S,S)-1,2-Bis[(tert-Butyl)Methylphosphino]Ethane[η-(2,5-Norbornadiene)]Rhodium(I) Tetrafluoroborate is a high-value, chiral organometallic complex widely recognized as a highly efficient and enantioselective catalyst precursor. Its primary value lies in enabling sophisticated asymmetric transformations, particularly hydrogenation reactions, which are critical for producing single-enantiomer intermediates in the pharmaceutical and fine chemical industries. This catalyst is essential for R&D chemists and process engineers working on the synthesis of chiral active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise stereochemical control is paramount.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective hydrogenation of prochiral olefins, enamides, and ketones to produce chiral building blocks.
• Pharmaceutical Intermediate Synthesis: Critical in the production of single-enantiomer APIs for cardiovascular, central nervous system, and antiviral drugs.
• Fine Chemical Manufacturing: Used in the synthesis of complex chiral molecules for flavors, fragrances, and advanced materials.
• Agrochemical Research: Employed in developing enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A key reagent for methodology development and exploring new asymmetric catalytic processes in both academic and industrial laboratories.
• Process Chemistry Optimization: Used for scaling up enantioselective reactions from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(S,S)-1,2-Bis[(tert-Butyl)Methylphosphino]Ethane[η-(2,5-Norbornadiene)]Rhodium(I) Tetrafluoroborate
CAS No.	203000-59-3
Molecular Formula	C₂₀H₃₈BF₄P₂Rh
Molecular Weight	530.17 g/mol
Synonyms	(S,S)-Et-DuPhos Rhodium(I) Tetrafluoroborate Norbornadiene Complex; (S,S)-1,2-Bis(tert-butylmethylphosphino)ethanerhodium(I) tetrafluoroborate; Rhodium, [(1,2,5,6-η)-bicyclo[2.2.1]hepta-2,5-diene][(2S,3S)-bis[(2-methyl-2-propanyl)methylphosphino]ethane]-, tetrafluoroborate(1-); (S,S)-Et-DuPhos-Rh(NBD)BF₄; (S,S)-Et-DuPhos(NBD)Rh⁺BF₄⁻; DuPhos Rhodium Catalyst; (S,S)-1,2-Bis((tert-butyl)methylphosphino)ethane(norbornadiene)rhodium tetrafluoroborate
EINECS	Contact for details

Quality Control

Our (S,S)-1,2-Bis[(tert-Butyl)Methylphosphino]Ethane[η-(2,5-Norbornadiene)]Rhodium(I) Tetrafluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and enantiomeric excess of the ligand. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to preserve catalytic activity.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	~19.4% (Theoretical)
Solubility	Soluble in dichloromethane, acetone; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.