Description

3-Chloro-5-Fluorophenol is a halogenated phenol derivative serving as a versatile and high-value organic intermediate. Its molecular structure, featuring both chlorine and fluorine substituents, makes it a critical building block for synthesizing advanced chemical compounds. This product is essential for research and development, as well as commercial-scale manufacturing, in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystal monomers used in display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyarylates and engineering plastics.
• Organic Synthesis: A valuable reagent for introducing the 3-chloro-5-fluorophenoxy group into more complex molecules via etherification or cross-coupling reactions.
• Dyestuff and Pigment Intermediate: Utilized in the manufacture of specialized dyes and pigments requiring halogenated phenolic components.

Basic Information

Item	Detail
Product Name	3-Chloro-5-Fluorophenol
CAS No.	202982-70-5
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	3-Chloro-5-fluorophenol; 5-Fluoro-3-chlorophenol; 3-Chloro-5-fluoro-1-hydroxybenzene; Phenol, 3-chloro-5-fluoro-; m-Chloro-m-fluorophenol
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation to maintain optimal quality. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.