Description

4-Chloro-3-Fluorobenzylamine Hydrochloride is a high-purity, halogenated benzylamine derivative offered as a stable hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile organic building block for synthesizing complex molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the chloro-fluoro aromatic system.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other synthetic transformations.
• Chemical Research & Development: Serves as a versatile starting material for medicinal chemistry, process chemistry, and the exploration of new chemical entities.
• Material Science: Potential monomer or functionalization agent in the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	4-Chloro-3-Fluorobenzylamine Hydrochloride
CAS No.	202982-64-7
Molecular Formula	C7H8ClFN • HCl
Molecular Weight	200.05 (Free base) / 236.51 (Hydrochloride)
Synonyms	1-(4-Chloro-3-fluorophenyl)methanamine hydrochloride; (4-Chloro-3-fluorobenzyl)amine hydrochloride; 4-Chloro-3-fluoro-benzenemethanamine hydrochloride; 3-Fluoro-4-chlorobenzylamine HCl; 4-Chloro-3-fluorobenzylammonium chloride; α-Amino-4-chloro-3-fluorotoluene hydrochloride; Benzenemethanamine, 4-chloro-3-fluoro-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.