Description

4-Chloro-2-Fluorobenzylamine Hydrochloride is a high-purity, versatile halogenated benzylamine derivative essential for advanced organic synthesis. This compound serves as a critical building block in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Chloro-2-Fluorobenzylamine Hydrochloride
CAS No.	202982-63-6
Molecular Formula	C7H8ClFN • HCl
Molecular Weight	204.05 g/mol (Free base: 159.59 g/mol)
Synonyms	(4-Chloro-2-fluorophenyl)methanamine hydrochloride; 1-(4-Chloro-2-fluorophenyl)methanamine hydrochloride; 2-Fluoro-4-chlorobenzylamine hydrochloride; 4-Chloro-2-fluoro-benzenemethanamine hydrochloride; Benzenemethanamine, 4-chloro-2-fluoro-, hydrochloride; α-Amino-4-chloro-2-fluorotoluene hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to meet stringent customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support development and commercial projects requiring compliance with ISO and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.