Description

5-Bromo-2-Fluorocinnamic Acid is a high-purity fluorinated and brominated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the halogen atoms for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated organic semiconductors and liquid crystal molecules due to its conjugated system and halogen substituents.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Biology Probes: Utilized in the synthesis of fluorescent tags and molecular probes for imaging and diagnostic applications.
• Polymer Modification: Incorporated into polymer backbones to impart specific properties like UV stability or altered solubility.

Basic Information

Product Name	5-Bromo-2-Fluorocinnamic Acid
CAS No.	202865-71-2
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	(E)-3-(5-Bromo-2-fluorophenyl)acrylic acid; 3-(5-Bromo-2-fluorophenyl)-2-propenoic acid; 2-Fluoro-5-bromocinnamic acid; trans-5-Bromo-2-fluorocinnamic acid; 5-Bromo-2-fluoro-trans-cinnamic acid; (2E)-3-(5-Bromo-2-fluorophenyl)prop-2-enoic acid; 202865-71-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.