Description

5-Bromo-2-Fluorobenzylamine Hydrochloride is a high-purity, halogenated benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, providing both a reactive amine group and halogen substituents for further cross-coupling and derivatization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the bromo and fluoro substituents modulate biological activity and stability.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and liquid crystals, where its aromatic core and halogen atoms influence material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	5-Bromo-2-Fluorobenzylamine Hydrochloride
CAS No.	202865-67-6
Molecular Formula	C7H8BrClFN
Molecular Weight	240.50 g/mol
Synonyms	1-(5-Bromo-2-fluorophenyl)methanamine hydrochloride; (5-Bromo-2-fluorobenzyl)amine hydrochloride; 5-Bromo-2-fluoro-benzenemethanamine hydrochloride; Benzenemethanamine, 5-bromo-2-fluoro-, hydrochloride; 2-Fluoro-5-bromobenzylamine HCl; α-Amino-5-bromo-2-fluorotoluene hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorobenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.