Description

1-(4-Nitrophenyl)Cyclobutanecarboxylic Acid is a specialized organic compound featuring a cyclobutane ring substituted with both a carboxylic acid and a nitrophenyl group. This unique structure makes it a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring constrained ring systems.
• Agrochemical Research: Used in developing new herbicides, fungicides, or insecticides where the nitrophenyl and carboxylic acid functionalities are critical for bioactivity.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialized polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic chemistry research for constructing complex carbocyclic frameworks and studying cyclobutane ring reactivity.
• Analytical Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for method development and validation.

Basic Information

Product Name	1-(4-Nitrophenyl)Cyclobutanecarboxylic Acid
CAS No.	202737-42-6
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	4-Nitro-α-phenylcyclobutanemethanol-α-carboxylic acid; Cyclobutanecarboxylic acid, 1-(4-nitrophenyl)-; 1-(p-Nitrophenyl)cyclobutanecarboxylic acid; 1-(4-Nitrophenyl)cyclobutane-1-carboxylic acid; p-Nitrophenylcyclobutanecarboxylic acid; 4-Nitrophenylcyclobutanecarboxylic acid; 202737-42-6; 1-(4-Nitrophenyl)-1-cyclobutanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Nitrophenyl)Cyclobutanecarboxylic Acid adheres to stringent GMP and ISO 9001 guidelines to ensure batch-to-batch consistency and traceability. Every lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.