Description

1-(2H-1,3-Benzodioxol-5-Yl)Cyclobutane-1-Carboxylic Acid is a high-value, synthetically derived organic compound featuring a cyclobutane carboxylic acid core linked to a benzodioxole moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides due to its complex bicyclic structure.
• Fine Chemical Production: Acts as a building block for synthesizing specialty chemicals, flavors, and fragrances.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel organic synthesis.
• Material Science: Investigated as a monomer or precursor for specialized polymers with unique thermal or optical properties.

Basic Information

Product Name	1-(2H-1,3-Benzodioxol-5-Yl)Cyclobutane-1-Carboxylic Acid
CAS No.	202737-28-8
Molecular Formula	C₁₂H₁₂O₄
Molecular Weight	220.22 g/mol
Synonyms	1-(1,3-Benzodioxol-5-yl)cyclobutanecarboxylic acid; 1-(2H-1,3-Benzodioxol-5-yl)cyclobutanecarboxylic acid; 1-(Benzo[d][1,3]dioxol-5-yl)cyclobutanecarboxylic acid; 5-(1-Carboxycyclobutyl)-1,3-benzodioxole; Cyclobutanecarboxylic acid, 1-(1,3-benzodioxol-5-yl)-; 202737-28-8
EINECS	Contact for details

Quality Control

Our production of 1-(2H-1,3-Benzodioxol-5-Yl)Cyclobutane-1-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP and ISO 9001 standards for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.