Description

(-)-5-Caffeoyl Quinic Acid CAS NO 202650-88-2 is a specific stereoisomer of chlorogenic acid, a key bioactive polyphenol found in plants like coffee beans and artichokes. This high-purity reference standard is essential for research and development, offering a defined chemical entity for accurate analytical work and biological studies. It is primarily sought by manufacturers and researchers in the nutraceutical, pharmaceutical, and cosmetic industries for its antioxidant and anti-inflammatory properties.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of chlorogenic acid in drug substances and herbal preparations.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into supplements targeting metabolic health, leveraging its well-researched antioxidant and potential glucose metabolism-modulating effects.
• Cosmetic & Skincare Active: Serves as a key active ingredient in anti-aging and protective formulations due to its ability to neutralize free radicals and mitigate oxidative stress on the skin.
• Food & Beverage Research: Employed in analytical laboratories to quantify chlorogenic acid content in coffee, fruits, and functional foods for quality control and labeling purposes.
• Academic & Biomedical Research: Utilized in in-vitro and in-vivo studies to investigate mechanisms of action related to neuroprotection, hepatoprotection, and metabolic syndrome.
• Natural Product Isolation & Synthesis: Acts as a critical intermediate or benchmark for the semi-synthesis of related caffeoylquinic acid derivatives.

Basic Information

Product Name	(-)-5-Caffeoyl Quinic Acid
CAS No.	202650-88-2
Molecular Formula	C16H18O9
Molecular Weight	354.31 g/mol
Synonyms	(-)-5-CQA; (1S,3R,4R,5R)-3-[[(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid; 5-O-Caffeoylquinic acid; Neochlorogenic acid (often refers to 5-CQA); 5-Caffeoylquinic Acid; Chlorogenic Acid (5-isomer); 5-CQA; 5-O-Caffeoyl-D-quinic acid
EINECS	Contact for details

Quality Control

Our (-)-5-Caffeoyl Quinic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets stringent specifications for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.