Description

2-Chloro-5-Fluorobenzylamine is a versatile halogenated benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive amine group and a halogen-substituted aromatic ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), crop protection agents, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used to create novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Material Science: Monomer or modifier in the production of specialty polymers, resins, and advanced functional materials.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new reaction pathways and heterocyclic compound synthesis.
• Fluorescent Probe and Dye Synthesis: Intermediate for creating fluorophores and imaging agents used in biochemical assays and diagnostics.

Basic Information

Product Name	2-Chloro-5-Fluorobenzylamine
CAS No.	202522-23-4
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(2-Chloro-5-fluorophenyl)methanamine; 1-(2-Chloro-5-fluorophenyl)methanamine; 2-Chloro-5-fluorobenzyl amine; 2-Chloro-5-fluoro-α-toluidine; Benzenemethanamine, 2-chloro-5-fluoro-; 2-Chloro-5-fluoro-1-methylaminebenzene; α-Amino-2-chloro-5-fluorotoluene; 5-Fluoro-2-chlorobenzylamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluorobenzylamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.