Description

n-(3,4-Dimethoxyphenyl)-6,7-Dimethoxyquinazolin-4-Amine is a high-purity quinazoline derivative, a key chemical intermediate prized for its role in advanced pharmaceutical synthesis. This compound matters because it provides a critical building block for developing targeted therapeutic agents, enabling precise molecular construction. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard and active scaffold in structure-activity relationship (SAR) studies and high-throughput screening.
• Organic Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• API Development: Employed in the research and development phase of new Active Pharmaceutical Ingredients (APIs), particularly those targeting tyrosine kinases.

Basic Information

Product Name	n-(3,4-Dimethoxyphenyl)-6,7-Dimethoxyquinazolin-4-Amine
CAS No.	202475-65-8
Molecular Formula	C20H21N3O4
Molecular Weight	367.40 g/mol
Synonyms	6,7-Dimethoxy-N-(3,4-dimethoxyphenyl)quinazolin-4-amine; 4-Amino-6,7-dimethoxyquinazoline N-(3,4-dimethoxyphenyl); 202475-65-8; 6,7-Dimethoxy-N-(3,4-dimethoxyphenyl)-4-quinazolinamine; 4-Quinazolinamine, 6,7-dimethoxy-N-(3,4-dimethoxyphenyl)-; N-(3,4-Dimethoxyphenyl)-6,7-dimethoxy-4-quinazolinamine
EINECS	Contact for details

Quality Control

Our n-(3,4-Dimethoxyphenyl)-6,7-Dimethoxyquinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under inert conditions if specified for high-purity grades to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.