Description

4-Chloro-7-Iodoquinazoline is a high-value halogenated quinazoline derivative, a crucial building block in modern pharmaceutical and agrochemical research. This compound matters for its role as a versatile synthetic intermediate, enabling the construction of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of kinase inhibitors and other active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tyrosine kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging the quinazoline core's bioactivity.
• Chemical Biology: Serves as a molecular scaffold or probe in the study of enzyme mechanisms and target identification.
• Material Science: Potential building block for organic electronic materials due to its conjugated heterocyclic structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	4-Chloro-7-Iodoquinazoline
CAS No.	202197-78-2
Molecular Formula	C8H4ClIN2
Molecular Weight	290.49 g/mol
Synonyms	7-Iodo-4-chloroquinazoline; 4-Chloro-7-iodo-quinazoline; Quinazoline, 4-chloro-7-iodo-; 202197-78-2; 4-Chloro-7-iodoquinazoline; 4-Chlor-7-jodchinazolin (German); 4-クロロ-7-ヨードキナゾリン (Japanese)
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Iodoquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.