Description

[1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of triazolopyrimidine-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for developing novel organic ligands, coordination polymers, and functional materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom and scale-up synthesis projects.

Basic Information

Product Name	[1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	202065-25-6
Molecular Formula	C6H4N4O2
Molecular Weight	164.12 g/mol
Synonyms	1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxylic acid; 2-(1,2,4-Triazolo[1,5-a]pyrimidin-2-yl)acetic acid (tautomer); TPCA-1 (common research abbreviation); Triazolopyrimidine-2-carboxylic acid; [1,2,4]Triazolopyrimidine-2-carboxylic acid; 1,2,4-Triazolo[1,5-a]pyrimidine-2-carboxylate; 2-Carboxy[1,2,4]triazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our [1,2,4]Triazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.