Description

H-Orn-Amc 2 Hcl is a specialized, high-purity chemical building block primarily used in advanced research and development. This compound is critical for the synthesis of complex peptides and other bioactive molecules, offering researchers precise control over molecular structure. It is particularly valuable for pharmaceutical R&D, biotechnology, and academic laboratories focused on protease substrate studies and enzyme inhibitor design.

Application

• Protease Substrate & Inhibitor Development: A key fluorogenic substrate (AMC derivative) for studying the activity and kinetics of various proteolytic enzymes.
• Pharmaceutical Research (R&D): Serves as a crucial intermediate in the discovery and synthesis of novel therapeutic peptides and enzyme-targeted drugs.
• Biochemical Assay Reagent: Used in high-throughput screening (HTS) assays to identify and characterize enzyme modulators.
• Peptide Chemistry & Synthesis: An important protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Diagnostic Kit Manufacturing: Incorporated into specialized diagnostic kits for detecting specific enzyme activities related to disease states.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental studies in biochemistry, enzymology, and medicinal chemistry.

Basic Information

Product Name	H-Orn-Amc 2 Hcl
CAS No.	201854-09-3
Molecular Formula	C15H21N3O3 • 2HCl
Molecular Weight	380.27 g/mol (Free base: 291.35)
Synonyms	H-Ornithine-AMC dihydrochloride; Nα-Boc-Nδ-Cbz-L-Ornithine-7-amido-4-methylcoumarin hydrochloride; Boc-Orn(Cbz)-AMC•2HCl; L-Ornithine, N2-[(1,1-dimethylethoxy)carbonyl]-N5-[(phenylmethoxy)carbonyl]-, 1-(7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-yl) ester, hydrochloride (1:2); AMC-labeled Ornithine derivative; Fluorogenic ornithine substrate.
EINECS	Contact for details

Quality Control

Every batch of H-Orn-Amc 2 Hcl is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency suitable for sensitive research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity (HPLC), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.