Description

4-(2-Boc-Amino-Pyridin-4-Yl)-Benzoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those targeting protein-protein interactions or requiring specific heterocyclic scaffolds.
• Peptidomimetic Chemistry: Used to incorporate modified amino acid residues into peptide chains, enhancing metabolic stability and bioavailability of peptide-based therapeutics.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality during complex synthetic sequences, allowing for selective deprotection.
• Ligand Synthesis for Drug Discovery: Employed in the construction of chemical libraries for high-throughput screening (HTS) to identify new lead compounds.
• Material Science Research: Can be utilized as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Serves as a valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	4-(2-Boc-Amino-Pyridin-4-Yl)-Benzoic Acid
CAS No.	201810-35-7
Molecular Formula	C18H20N2O4
Molecular Weight	328.37 g/mol
Synonyms	4-(2-((tert-Butoxycarbonyl)amino)pyridin-4-yl)benzoic acid; 4-[2-[(tert-Butoxycarbonyl)amino]-4-pyridyl]benzoic Acid; 4-(2-Boc-amino-4-pyridinyl)benzoic acid; 4-(2-(Boc-amino)pyridin-4-yl)benzoic acid; Benzoic acid, 4-[2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-pyridinyl]-; 4-(2-(tert-Butoxycarbonylamino)pyridin-4-yl)benzoic acid; 4-(2-Boc-aminopyridin-4-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Boc-Amino-Pyridin-4-Yl)-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.