Description

3',4'-Dihydro-1'H-Spiro[Cyclohexane-1,2'-Quinolin]-7'-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic quinoline structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, anti-inflammatory drugs, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct intricate molecular architectures due to its spirocyclic core.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Agrochemical Research: May be investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Material Science Exploration: The fused ring system can be explored for creating organic electronic materials or ligands for catalysis.

Basic Information

Product Name	3',4'-Dihydro-1'H-Spiro[Cyclohexane-1,2'-Quinolin]-7'-Amine
CAS No.	201654-33-3
Molecular Formula	C14H18N2
Molecular Weight	214.31 g/mol
Synonyms	7'-Amino-3',4'-dihydro-1'H-spiro[cyclohexane-1,2'-quinoline]; Spiro[cyclohexane-1,2'(1'H)-quinolin]-7'-amine, 3',4'-dihydro-; 1'H-Spiro[cyclohexane-1,2'-quinolin]-7'-amine, 3',4'-dihydro-; 3',4'-Dihydrospiro[cyclohexane-1,2'(1'H)-quinolin]-7'-amine; 7-Aminospiro[cyclohexane-1,2'(1'H)-quinoline]; CAS 201654-33-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates to support our global clientele's regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.