Description

n-Me-Allo-Ile-Obzl p-Tosylate is a high-purity, non-natural amino acid derivative, specifically a protected form of allo-isoleucine. This compound is a critical building block in advanced pharmaceutical research and peptide synthesis, offering precise stereochemical control for developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based drugs, metabolic studies, and complex organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Chemistry Research: Used in solid-phase and solution-phase peptide synthesis to introduce modified isoleucine residues, enabling structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Acts as a core component in designing inhibitors for specific enzymes due to its unique allo-configuration and protected functional groups.
• Chemical Biology Probes: Incorporated into peptide probes for investigating protein-protein interactions and cellular signaling pathways.
• Academic & Industrial R&D: Employed in research laboratories for methodological development in asymmetric synthesis and exploring new synthetic routes.

Basic Information

Product Name	n-Me-Allo-Ile-Obzl p-Tosylate
CAS No.	201544-39-0
Molecular Formula	C24H33NO6S
Molecular Weight	463.59 g/mol
Synonyms	N-Methyl-allo-isoleucine benzyl ester p-toluenesulfonate salt; (2S,3S)-2-(Benzyloxycarbonyl(methyl)amino)-3-methylpentanoic acid 4-methylbenzenesulfonate; allo-N-Me-Ile-OBzl Tosylate; Benzyl N-methyl-L-allo-isoleucinate p-toluenesulfonate; Z-N-Me-allo-Ile-OBzl Tos; N-Methyl-L-allo-isoleucine benzyl ester tosylate salt; (2S,3S)-2-[[(Benzyloxy)carbonyl](methyl)amino]-3-methylpentanoic acid 4-methylbenzenesulfonic acid
EINECS	Contact for details

Quality Control

Our n-Me-Allo-Ile-Obzl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR/IR for structural confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.