Description

trans-2-(4-Chlorobenzoyl)Cyclohexane-1-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where structural precision is paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex molecular architectures, leveraging the reactivity of both the carboxylic acid and ketone functional groups.
• Agrochemical Research: Serves as a precursor in the development of new generation herbicides and pesticides with enhanced efficacy and selectivity.
• Material Science: Investigated for the synthesis of specialized monomers and ligands for catalysts or advanced polymeric materials.

Basic Information

Product Name	trans-2-(4-Chlorobenzoyl)Cyclohexane-1-Carboxylic Acid
CAS No.	201027-60-3
Molecular Formula	C14H15ClO3
Molecular Weight	266.72 g/mol
Synonyms	2-[(4-Chlorophenyl)carbonyl]cyclohexane-1-carboxylic acid (trans-); (1R,2S)-rel-2-(4-Chlorobenzoyl)cyclohexanecarboxylic acid; trans-2-(p-Chlorobenzoyl)cyclohexanecarboxylic Acid; 4'-Chloro-2-oxocyclohexanecarboxylic acid phenyl ketone; 201027-60-3; Cyclohexanecarboxylic acid, 2-(4-chlorobenzoyl)-, trans-; p-Chloro-trans-α-oxocyclohexanephenylacetic acid
EINECS	Contact for details

Quality Control

Our trans-2-(4-Chlorobenzoyl)Cyclohexane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.