Description

2-Bromo-4-(Trifluoromethoxy)Phenol is a versatile halogenated phenol derivative, distinguished by its bromine and trifluoromethoxy substituents. This compound is a critical high-purity intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences and crop protection industries for constructing complex aromatic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the phenol and halogenated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to introduce functionalized phenolic groups.
• Chemical Research: A valuable reference standard and starting material in academic and industrial laboratories for exploring new synthetic methodologies.

Basic Information

Item	Detail
Product Name	2-Bromo-4-(Trifluoromethoxy)Phenol
CAS No.	200956-13-4
Molecular Formula	C7H4BrF3O2
Molecular Weight	257.01 g/mol
Synonyms	2-Bromo-4-(trifluoromethoxy)phenol; 4-Trifluoromethoxy-2-bromophenol; Phenol, 2-bromo-4-(trifluoromethoxy)-; 2-Bromo-4-trifluoromethoxyphenol; 2-Bromo-α,α,α-trifluoro-p-cresol ether; 2-Bromo-4-(trifluoromethyloxy)phenol; 2-Bromo-4-(perfluoromethyloxy)phenol; 2-Bromophenol, 4-trifluoromethoxy derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethoxy)Phenol is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including HPLC, GC, and NMR data, to guarantee identity, purity, and consistency. A Certificate of Analysis (COA) is supplied with each shipment, and our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.