Description

4-Oxo-4-(2-Trifluoromethylphenyl)Butyric Acid is a high-purity, versatile organic intermediate featuring a trifluoromethylphenyl ketone moiety. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Oxo-4-(2-Trifluoromethylphenyl)Butyric Acid
CAS No.	200725-09-3
Molecular Formula	C11H9F3O3
Molecular Weight	246.18 g/mol
Synonyms	4-(2-Trifluoromethylbenzoyl)butyric Acid; 4-Oxo-4-[2-(trifluoromethyl)phenyl]butanoic Acid; γ-Oxo-2-(trifluoromethyl)benzenebutanoic Acid; 4-(2-(Trifluoromethyl)benzoyl)butanoic Acid; 2-Trifluoromethyl-γ-oxobenzenebutanoic Acid; Butanoic acid, 4-oxo-4-[2-(trifluoromethyl)phenyl]-; 200725-09-3
EINECS	Contact for details

Quality Control

Our 4-Oxo-4-(2-Trifluoromethylphenyl)Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.