Description

tert-Butyl (2-((tert-Butoxycarbonyl)Amino)Ethyl)(2-Hydroxyethyl)Carbamate is a specialized Boc-protected amino alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing orthogonal protection for amine and alcohol functionalities, enabling precise, multi-step molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly for oncology and central nervous system (CNS) therapies.
• Peptide & Peptidomimetic Synthesis: Used to introduce protected amino alcohol side chains, facilitating the creation of novel peptide structures with enhanced stability and bioavailability.
• Linker Chemistry for Bioconjugation: Serves as a functional spacer or linker molecule in the development of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Protecting Group Strategy: Enables selective deprotection sequences in multi-functional molecule synthesis, crucial for medicinal chemistry and process development.
• Chemical Biology Probe Development: Utilized in the construction of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the global pharmaceutical and agrochemical industries.

Basic Information

Product Name	tert-Butyl (2-((tert-Butoxycarbonyl)Amino)Ethyl)(2-Hydroxyethyl)Carbamate
CAS No.	200283-08-5
Molecular Formula	C14H28N2O5
Molecular Weight	304.38 g/mol
Synonyms	Boc-NH-CH2-CH2-N(Boc)-CH2-CH2-OH; 2-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)(2-hydroxyethyl)carbamoyl]oxy-2-methylpropane; 1,1-Dimethylethyl N-[2-[[(1,1-dimethylethoxy)carbonyl](2-hydroxyethyl)amino]ethyl]carbamate; N-Boc-ethanolamine-N-Boc-ethylamine; tert-Butyl N-[2-({[(tert-butoxy)carbonyl](2-hydroxyethyl)amino})ethyl]carbamate; Di-Boc Protected Amino Alcohol; 2,2'-((((tert-Butoxycarbonyl)azanediyl)bis(ethane-2,1-diyl))bis(oxy))bis(2-methylpropane) (alternative IUPAC); Boc-AEEA(Boc)-OH (common abbreviation)
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-((tert-Butoxycarbonyl)Amino)Ethyl)(2-Hydroxyethyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.