Description

1,4-Bis(Diphenylphosphino)Butane-Palladium(II) Chloride is a highly active and versatile palladium-based catalyst complex, essential for facilitating critical cross-coupling reactions in organic synthesis. Its value lies in providing a stable, pre-formed catalytic system that offers superior reactivity and selectivity compared to in-situ prepared catalysts, streamlining research and production processes. This product is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling: A key catalyst for forming carbon-carbon bonds between aryl/vinyl boronic acids and aryl/vinyl halides, a cornerstone reaction in pharmaceutical synthesis.
• Heck Reaction (Mizoroki-Heck): Catalyzes the coupling of aryl halides or triflates with alkenes to form substituted alkenes, crucial for creating complex molecular frameworks.
• Sonogashira Coupling: Enables the coupling of terminal alkynes with aryl or vinyl halides to construct conjugated enynes and arylalkynes, important in material science and drug discovery.
• Buchwald-Hartwig Amination: Facilitates the formation of carbon-nitrogen bonds for synthesizing aryl amines, which are prevalent in many drug molecules and functional materials.
• Homogeneous Catalysis Research: Serves as a standard, well-defined catalyst for method development and mechanistic studies in academic and industrial research settings.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, liquid crystals, and organic electronic materials where precise molecular architecture is required.

Basic Information

Item	Details
Product Name	1,4-Bis(Diphenylphosphino)Butane-Palladium(II) Chloride
CAS No.	29964-62-3
Molecular Formula	C28H28Cl2P2Pd
Molecular Weight	604.77 g/mol
Synonyms	1,4-Bis(diphenylphosphino)butane palladium(II) chloride; DPPB-PdCl2; Pd(dppb)Cl2; [1,4-Bis(diphenylphosphino)butane]dichloropalladium; Palladium(II) chloride bis(diphenylphosphino)butane complex; Palladium(II) chloride-1,4-bis(diphenylphosphino)butane; 1,4-Bis(diphenylphosphanyl)butane-palladium dichloride
EINECS	Contact for details

Quality Control

Our 1,4-Bis(Diphenylphosphino)Butane-Palladium(II) Chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including assay (Pd content), purity assessment via NMR and HPLC, and verification of ligand-to-metal stoichiometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd Content)	≥ 17.5 %
Purity (HPLC)	≥ 98.0 %
Solubility	Soluble in dichloromethane, chloroform; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.