Description

6-Methylcholanthrene CAS NO 29873-25-4 is a high-purity polycyclic aromatic hydrocarbon (PAH) derivative of significant interest in biochemical and toxicological research. This compound is a potent carcinogen and mutagen, making it a critical reference standard and tool for studying cancer mechanisms, metabolic activation pathways, and DNA adduct formation. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and environmental testing facilities engaged in toxicology, oncology, and chemical safety assessment.

Application

• Biomedical Research: Used as a potent carcinogenic agent in experimental models to study tumor initiation, promotion, and progression.
• Toxicology Studies: Serves as a key reference standard for investigating the metabolic activation, genotoxicity, and mutagenicity of polycyclic aromatic hydrocarbons (PAHs).
• Oncology Research: Employed in mechanistic studies to understand DNA damage, repair mechanisms, and cellular transformation.
• Environmental Analysis: Acts as a calibration standard in analytical methods (e.g., HPLC, GC-MS) for detecting and quantifying PAHs in environmental samples.
• Chemical Safety Assessment: Used in regulatory and safety testing to evaluate the carcinogenic potential of complex chemical mixtures.
• Pharmaceutical Development: Utilized in early-stage drug discovery to screen for chemopreventive agents or compounds that inhibit metabolic activation of procarcinogens.

Basic Information

Product Name	6-Methylcholanthrene
CAS No.	29873-25-4
Molecular Formula	C21H16
Molecular Weight	268.36 g/mol
Synonyms	6-MCA; 6-Methyl-1,2-benzanthracene; 3-Methylcholanthrene (common misnomer); 20-Methylcholanthrene; 1,2-Dihydro-3-methylbenz[j]aceanthrylene; NSC 21914; 6-Methyl-1,2-benzanthracene
EINECS	Contact for details

Quality Control

Our 6-Methylcholanthrene is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	178°C - 182°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.