Description

1-(Iodomethyl)-2-Nitrobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electrophilic iodomethyl group and a nitro substituent, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as an intermediate for active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring benzyl-modified structures.
• Agrochemical Synthesis: Used in the research and development of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed reactions, such as Suzuki, Negishi, or Stille couplings, to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized for the preparation of complex ligands and organocatalysts used in asymmetric synthesis.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized nitroaromatic dyes and colorants.

Basic Information

Product Name	1-(Iodomethyl)-2-Nitrobenzene
CAS No.	29872-21-7
Molecular Formula	C7H6INO2
Molecular Weight	263.03 g/mol
Synonyms	2-Nitrobenzyl Iodide; α-Iodo-2-nitrotoluene; (2-Nitrophenyl)methyl Iodide; 2-Nitrobenzyl Iodide; o-Nitrobenzyl Iodide; 1-Iodomethyl-2-nitrobenzene; (2-Nitrobenzyl) Iodide; Iodomethyl Nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-(Iodomethyl)-2-Nitrobenzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.