Description

3-Acetylnoradamantane is a high-purity, functionalized noradamantane derivative characterized by its unique bridged-ring structure and ketone functionality. This compound serves as a valuable and versatile advanced pharmaceutical intermediate and a sophisticated building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel molecular architectures with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, due to the noradamantane scaffold's ability to enhance lipophilicity and metabolic stability.
• Agrochemical Research: Used in the synthesis of new-generation pesticides and herbicides, where its rigid structure can contribute to improved binding affinity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or as a backbone for organocatalysts, leveraging its three-dimensional geometry.
• Material Science Precursor: Employed in the synthesis of monomers for high-performance polymers or additives that can impart unique thermal and mechanical properties to advanced materials.
• Organic Synthesis Building Block: Utilized in method development and complex molecule synthesis, including natural product analogs, where its ketone group allows for further functionalization (e.g., reduction, Grignard reactions).
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical development.

Basic Information

Item	Detail
Product Name	3-Acetylnoradamantane
CAS No.	29844-80-2
Molecular Formula	C12H18O
Molecular Weight	178.27 g/mol
Synonyms	1-(3-Noradamantyl)ethanone; 3-Noradamantan-1-yl methyl ketone; 3-Acetyltricyclo[3.3.1.13,7]decane; 3-Acetyl-1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane (related heterocyclic system); Noradamantane-3-acetone; 3-Ketonoradamantane; 3-Acetyl-adamantane derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Acetylnoradamane is manufactured under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your internal and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.