Description

trans-2,4-Dimethyloxetane is a high-purity, versatile oxetane derivative, a valuable heterocyclic building block in advanced organic synthesis. Its strained four-membered ring structure makes it a key intermediate for constructing complex molecules with specific stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its oxetane ring contributes to biological activity and metabolic stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with unique properties like enhanced thermal stability, low shrinkage, and specific refractive indices.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Acts as a building block for fragrances, flavors, and other high-value fine chemicals requiring precise stereochemical control.

Basic Information

Item	Details
Product Name	trans-2,4-Dimethyloxetane
CAS No.	29424-94-0
Molecular Formula	C5H10O
Molecular Weight	86.13 g/mol
Synonyms	(2R,4S)-2,4-Dimethyloxetane; (2S,4R)-2,4-Dimethyloxetane; trans-2,4-Dimethyl-1,3-propylene oxide; 2,4-Dimethyloxacyclobutane; Oxetane, 2,4-dimethyl-, trans-; 2,4-Dimethyloxetane (trans isomer)
EINECS	Contact for details

Quality Control

Our trans-2,4-Dimethyloxetane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and isomeric integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize volatility and oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isomeric Purity (trans-)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.