Description

2-Methyl-3H-Quinazolin-4-One Hydrochloride is a high-purity organic salt derivative of a quinazolinone core, a privileged scaffold in medicinal chemistry. This compound is valued for its role as a critical synthetic intermediate and building block in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities based on the quinazolinone pharmacophore.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.

Basic Information

Product Name	2-Methyl-3H-Quinazolin-4-One Hydrochloride
CAS No.	29378-39-0
Molecular Formula	C9H9N2O·HCl
Molecular Weight	196.64 g/mol
Synonyms	2-Methyl-4(3H)-quinazolinone hydrochloride; 2-Methyl-3,4-dihydro-4-oxoquinazoline hydrochloride; 2-Methyl-4-hydroxyquinazoline hydrochloride; 4(3H)-Quinazolinone, 2-methyl-, hydrochloride; 2-Methylquinazolin-4(3H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-3H-Quinazolin-4-One Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.