Description

(1S,2R)-cis-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its defined stereochemistry makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and cardiovascular medications.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for enantioselective catalysis in organic synthesis.
• Agrochemical Research: Serves as a building block for creating chiral active ingredients in advanced crop protection products.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring precise stereocontrol.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes to chiral targets in pilot plant and manufacturing settings.

Basic Information

Product Name	(1S,2R)-cis-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride
CAS No.	29365-58-0
Molecular Formula	C₁₀H₁₄ClNO
Molecular Weight	199.68 g/mol
Synonyms	(1S,2R)-2-Amino-1,2,3,4-tetrahydro-1-naphthol hydrochloride; cis-2-Amino-1,2,3,4-tetrahydro-1-naphthol hydrochloride; (1S,2R)-1,2,3,4-Tetrahydro-2-amino-1-naphthol HCl; 1,2,3,4-Tetrahydro-2-amino-1-naphthol hydrochloride (cis-); 2-Amino-1,2,3,4-tetrahydro-1-naphthalenol hydrochloride; (1S,2R)-Aminotetralin hydrochloride derivative
EINECS	Contact for details

Quality Control

Our (1S,2R)-cis-2-Amino-1,2,3,4-Tetrahydro-1-Naphthol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.