Description

S-2-Chloro-2-Phenylacetic Acid is a chiral organic acid derivative of significant interest in fine chemical synthesis. Its core value lies in its utility as a versatile building block for constructing more complex, optically active molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific enantiomer can influence efficacy and environmental safety.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or auxiliaries used in asymmetric synthesis to induce enantioselectivity.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Peptide Modification: Can be used to introduce chiral, halogenated phenylacetic acid moieties into peptide chains for structure-activity relationship (SAR) studies.

Basic Information

Product Name	S-2-Chloro-2-Phenylacetic Acid
CAS No.	29125-24-4
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	(S)-2-Chloro-2-phenylacetic acid; (S)-α-Chlorophenylacetic acid; (S)-CPA; L-2-Chloro-2-phenylacetic acid; (S)-2-Chloro-2-phenylethanoic acid; (S)-O-Chloromandelic acid; (2S)-2-Chloro-2-phenylacetic acid
EINECS	Contact for details

Quality Control

Our S-2-Chloro-2-Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.