Description

2-Fluoro-4-isopropoxy-1-nitrobenzene is a specialized fluorinated aromatic nitro compound that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and an isopropoxy group ortho to a nitro substituent, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This intermediate is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Dye & Pigment Precursor: Employed in the synthesis of specialized dyes and pigments, where the nitro group can be further functionalized.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Fluoro-4-Isopropoxy-1-Nitrobenzene
CAS No.	28987-50-0
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	1-Fluoro-2-nitro-4-isopropoxybenzene; 2-Fluoro-4-isopropoxynitrobenzene; 4-Isopropoxy-2-fluoronitrobenzene; Benzene, 2-fluoro-4-isopropoxy-1-nitro-; 2-Fluoro-4-(1-methylethoxy)-1-nitrobenzene; 1-Nitro-2-fluoro-4-isopropoxybenzene
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-4-isopropoxy-1-nitrobenzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.