Description

1-(Prop-2-Yn-1-Yl)Quinazolin-4(1H)-One is a specialized quinazolinone derivative featuring a propargyl functional group, making it a valuable synthetic intermediate for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and agrochemicals, where its unique scaffold enables the construction of complex molecular architectures. It is primarily utilized in medicinal chemistry R&D, pharmaceutical process development, and the synthesis of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the quinazolinone core for bioactivity.
• Organic Synthesis Reagent: Acts as a versatile precursor for click chemistry reactions via its alkyne group, facilitating the creation of complex molecular libraries.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialized polymers and advanced organic materials.
• Bioconjugation Chemistry: The propargyl moiety allows for efficient labeling and conjugation strategies in probe and diagnostic agent development.

Basic Information

Product Name	1-(Prop-2-Yn-1-Yl)Quinazolin-4(1H)-One
CAS No.	28899-22-1
Molecular Formula	C₁₁H₈N₂O
Molecular Weight	184.20 g/mol
Synonyms	1-(Prop-2-yn-1-yl)-1,4-dihydroquinazolin-4-one; 1-Propargylquinazolin-4(1H)-one; 4(1H)-Quinazolinone, 1-(2-propynyl)-; 1-(2-Propynyl)-4(1H)-quinazolinone; Quinazolin-4(1H)-one, 1-(2-propynyl)-; 1-(Prop-2-ynyl)quinazolin-4(1H)-one; 28899-22-1
EINECS	Contact for details

Quality Control

Our 1-(Prop-2-Yn-1-Yl)Quinazolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.