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Sodium L-Pyroglutamate CAS NO 28874-51-3
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CAS No.:28874-51-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Sodium L-Pyroglutamate is the sodium salt of the naturally occurring amino acid derivative L-pyroglutamic acid. This high-purity compound is valued for its role as a versatile intermediate and functional ingredient in advanced synthesis and formulation. It is essential for manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries seeking reliable, high-quality raw materials for research and production.
Application
- Pharmaceutical Intermediate: Used in the synthesis of various active pharmaceutical ingredients (APIs) and prodrugs.
- Cosmetic & Personal Care: Functions as a skin-conditioning agent and moisturizer in anti-aging creams, lotions, and serums.
- Nutraceutical & Dietary Supplements: Employed as a component in nootropic and cognitive health formulations.
- Biochemical Research: Serves as a reagent and standard in metabolic pathway studies and analytical chemistry.
- Flavor & Fragrance Industry: Acts as a precursor or modifier in the creation of specific savory flavor profiles (umami).
- Cell Culture Media: Used as an additive in certain specialized cell culture and fermentation processes.
Basic Information
| Product Name | Sodium L-Pyroglutamate |
| CAS No. | 28874-51-3 |
| Molecular Formula | C5H6NNaO3 |
| Molecular Weight | 151.10 g/mol |
| Synonyms | L-Pyroglutamic Acid Sodium Salt; Sodium (S)-5-Oxopyrrolidine-2-carboxylate; Sodium 5-Oxoproline; L-2-Pyrrolidone-5-carboxylic Acid Sodium Salt; PCA Sodium Salt; Sodium PCA; (S)-5-Oxo-2-pyrrolidinecarboxylic Acid Sodium Salt; Glutamic Acid 5-Lactam Sodium Salt |
| EINECS | 249-277-1 |
Quality Control
Our Sodium L-Pyroglutamate is manufactured under a strict quality management system. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and cosmetic applications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with every shipment to guarantee traceability and compliance.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Specific Rotation [α]20/D | -10.0° to -14.0° (c=1 in H2O) |
| pH (5% solution) | 6.0 - 8.0 |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition (Sulfated Ash) | 28.0% - 32.0% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






