Description

(+)-Nootkatone CAS NO 28834-25-5 is a premium, naturally-derived sesquiterpenoid ketone renowned for its distinctive grapefruit aroma and potent bioactivity. This high-value compound is critical for industries requiring authentic, powerful, and natural flavor and fragrance profiles. It is essential for manufacturers in the flavor & fragrance, food & beverage, and agrochemical sectors seeking effective, nature-identical ingredients for premium product formulations.

Application

• Flavor & Fragrance Industry: A key high-impact ingredient for creating authentic grapefruit, citrus, and woody notes in perfumes, colognes, fine fragrances, and personal care products.
• Food & Beverage Enhancement: Used as a natural flavoring agent (FEMA GRAS) to impart fresh, bitter-citrus character to beverages, confectionery, and dairy products.
• Natural Insect Repellent & Pesticide: Serves as an active ingredient in EPA-registered, bio-based repellents and pesticides targeting mosquitoes, ticks, and other pests, valued for its non-toxic profile.
• Functional Food & Nutraceuticals: Incorporated into dietary supplements for its researched potential in supporting metabolic health and cognitive function.
• Aromatherapy & Wellness Products: Used in diffuser blends, candles, and topical wellness preparations for its uplifting and invigorating aromatic properties.
• Pharmaceutical Intermediates: Acts as a chiral building block or starting material in the synthesis of more complex therapeutic compounds.

Basic Information

Product Name	(+)-Nootkatone
CAS No.	28834-25-5
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	(+)-Nootkatone; (4R,4aS,6R)-4,4a,5,6,7,8-Hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-2(3H)-naphthalenone; (6R,10S)-6,10-Dimethylbicyclo[4.4.0]dec-1-en-3-one; Nootkatone; Nootkaton; Grapefruit Ketone; 5,6-Dimethyl-8-isopropenylbicyclo[4.4.0]dec-1-en-3-one
EINECS	249-277-1

Quality Control

Our (+)-Nootkatone is produced and tested under strict quality management systems to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical assay, and residual solvents. Our quality standards align with industry requirements for flavor (FEMA), fragrance (IFRA), and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, maintaining an inert atmosphere (e.g., under nitrogen) is recommended to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / crystals
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% (+)-enantiomer
Specific Rotation [α]20/D	+170° to +185° (c=1 in ethanol)
Refractive Index n20/D	1.508 - 1.512
Relative Density	0.992 - 0.998
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.