Description

D-Glucose-[1-3H(N)] CAS NO 28823-03-2 is a tritium-labeled isotopologue of D-glucose, a fundamental carbohydrate used in metabolic research. This labeled compound is essential for tracing and quantifying glucose uptake, transport, and metabolic flux in biological systems with high sensitivity. It is a critical reagent for researchers in pharmaceutical development, biochemistry, and metabolic disease studies who require precise, reliable tracers for in vitro and in vivo applications.

Application

• Metabolic Pathway Tracing: Used as a radioactive tracer to study glycolysis, gluconeogenesis, and the pentose phosphate pathway in cell cultures and tissues.
• Drug Discovery & Development: Employed in high-throughput screening assays to evaluate the effects of novel compounds on cellular glucose metabolism.
• Biochemical Research: Serves as a substrate for enzymatic studies of hexokinase, glucose-6-phosphate dehydrogenase, and other glucose-metabolizing enzymes.
• Diagnostic Probe Development: Utilized in the research and development of diagnostic agents for imaging glucose utilization, such as in cancer research.
• Pharmacokinetic Studies: Applied in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to track the metabolic fate of co-administered drugs.
• Nutritional Science: Used to investigate intestinal glucose absorption and whole-body glucose homeostasis in animal models.

Basic Information

Product Name	D-Glucose-[1-3H(N)]
CAS No.	28823-03-2
Molecular Formula	C6H113HO6
Molecular Weight	183.15 g/mol (for unlabeled D-glucose; exact mass varies with isotopic enrichment)
Synonyms	1-Tritio-D-glucose; [1-3H]-D-Glucose; D-Glucose (1-tritiated); Tritiated D-glucose; D-(+)-Glucose-[1-3H]; Glucose-1-t; Radiolabeled D-glucose; Deuterated glucose analog (tritium)
EINECS	Contact for details

Quality Control

Every batch of D-Glucose-[1-3H(N)] is manufactured and analyzed under strict quality systems. We guarantee high radiochemical purity and specific activity as specified for your research grade. Identity is confirmed by co-chromatography with an authentic standard. Our quality commitment includes comprehensive documentation, and a detailed Certificate of Analysis (COA) specifying radioactivity concentration, radiochemical purity, and solvent composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the solution at or below -20°C. The product is light-sensitive (store away from light). Always adhere to local regulations for the safe storage and handling of radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless solution
Identification (HPLC/TLC)	Co-elutes with reference standard
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	10-40 Ci/mmol (Contact for specific value)
Radioactivity Concentration	1 mCi/mL (Specified on COA)
Solvent	Ethanol:Water (9:1) or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.