Description

1,1-(Ethylenebisthio)-5α-Cholestan-19-Oic Acid Methyl Ester is a high-purity, synthetic steroid derivative characterized by its unique ethylene dithioacetal functionalization. This compound is a critical advanced intermediate in the synthesis of complex steroidal pharmaceuticals and fine chemicals, offering a versatile chemical handle for further functionalization. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for studying steroidal metabolism and receptor interactions.
• Fine Chemical Synthesis: Serves as a precursor for creating specialized steroidal compounds with modified biological activity.
• Reference Standard: Employed as an analytical standard in quality control and method development for steroidal analysis.

Basic Information

Product Name	1,1-(Ethylenebisthio)-5α-Cholestan-19-Oic Acid Methyl Ester
CAS No.	28809-63-4
Molecular Formula	C₃₁H₅₂O₂S₂
Molecular Weight	520.87 g/mol
Synonyms	Methyl 1,1-(ethylenedithio)-5α-cholestan-19-oate; 5α-Cholestan-19-oic acid, 1,1-(ethylenedithio)-, methyl ester; 19-Carbomethoxy-5α-cholestane-1,1-ethylenedithioketal; 1,1-Ethylenedithio-5α-cholestan-19-oic acid methyl ester; Methyl 19-carboxy-5α-cholestane-1,1-ethylenedithioketal
EINECS	Contact for details

Quality Control

Our 1,1-(Ethylenebisthio)-5α-Cholestan-19-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.