Description

Nordihydrocapsaicin CAS NO 28789-35-7 is a capsaicinoid, a naturally occurring analog of capsaicin found in chili peppers. This compound is valued for its role in the study of TRPV1 receptor activity and its contribution to the overall pungency and sensory profile of capsaicin mixtures. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences and flavor & fragrance industries. Key applications include analytical research, sensory science, and the development of specialized food ingredients and topical formulations.

Application

• Analytical Reference Standard: Used as a high-purity calibrant in HPLC, LC-MS, and GC-MS for the quantification of capsaicinoids in food, botanical extracts, and pharmaceutical products.
• Neuroscience & Pharmacology Research: A vital tool for studying the structure-activity relationship of vanilloid compounds and their interaction with the TRPV1 (vanilloid receptor 1) ion channel.
• Food Science & Sensory Analysis: Employed to modulate and study the precise pungency, heat profile, and flavor characteristics of chili-based products and spicy food formulations.
• Pharmaceutical Intermediate: Serves as a key synthetic building block or active ingredient in the development of topical analgesics, creams, and patches for pain management.
• Natural Product Isolation & Standardization: Essential for the quality control and standardization of chili pepper oleoresins and other capsaicin-rich botanical ingredients.
• Biochemical Research: Utilized in assays to investigate cellular responses to capsaicinoid exposure, including calcium influx and neurotransmitter release studies.

Basic Information

Product Name	Nordihydrocapsaicin
CAS No.	28789-35-7
Molecular Formula	C17H27NO3
Molecular Weight	293.40 g/mol
Synonyms	Nordihydrocapsaicin; (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; Dihydrocapsaicin II; Nonivamide analog; NDHC; Capsaicinoid II; 8-Methyl-N-vanillyl-6-nonenamide; Nonanoic acid vanillylamide derivative
EINECS	Contact for details

Quality Control

Our Nordihydrocapsaicin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.