Description

Chrysene-3,4-Dihydrodiol is a high-purity polycyclic aromatic hydrocarbon (PAH) metabolite and a key intermediate in the study of carcinogenic pathways. This compound is of significant value for researchers and industrial laboratories investigating the metabolic activation and detoxification mechanisms of environmental pollutants. It serves as a critical reference standard and synthetic building block for toxicology studies, environmental monitoring, and advanced material science applications.

Application

• Toxicology & Carcinogenesis Research: Used as a reference standard and metabolic intermediate in studies of PAH-induced DNA adduct formation and cancer bioassays.
• Environmental Analysis: Serves as a crucial analytical standard for the detection and quantification of chrysene metabolites in soil, water, and air pollution studies.
• Biochemical Research: Employed in enzymatic studies, particularly with cytochrome P450 and epoxide hydrolase, to understand the metabolic fate of chrysene.
• Pharmaceutical Development: Acts as a precursor or intermediate in the synthesis of compounds for investigating chemopreventive agents.
• Material Science: Potential use as a specialized organic building block for the synthesis of novel aromatic compounds and advanced materials.
• Regulatory & Compliance Testing: Essential for calibrating equipment and validating methods in laboratories performing regulatory analysis of PAHs and their derivatives.

Basic Information

Product Name	Chrysene-3,4-Dihydrodiol
CAS No.	28622-72-2
Molecular Formula	C₁₈H₁₄O₂
Molecular Weight	262.30 g/mol
Synonyms	3,4-Dihydroxy-3,4-dihydrochrysene; Chrysene 3,4-dihydrodiol; 3,4-Dihydrochrysene-3,4-diol; trans-Chrysene-3,4-dihydrodiol; (+/-)-trans-3,4-Dihydroxy-3,4-dihydrochrysene; Benz[a]phenanthrene-3,4-dihydrodiol; 3,4-Dihydroxy-1,2,3,4-tetrahydrochrysene
EINECS	Contact for details

Quality Control

Our Chrysene-3,4-Dihydrodiol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.