Description

Chrysene-1,2-Dihydrodiol CAS NO 28622-71-1 is a high-purity polycyclic aromatic hydrocarbon (PAH) metabolite, specifically a dihydrodiol derivative of chrysene. This compound is of significant value as a critical reference standard and biochemical intermediate in advanced research and analytical workflows. It is primarily required by pharmaceutical R&D laboratories, environmental testing facilities, and academic research institutions studying PAH metabolism, carcinogenesis, and bioremediation pathways.

Application

• Analytical Reference Standard: Used as a certified standard in HPLC, GC-MS, and LC-MS for the quantification and identification of chrysene metabolites in complex matrices.
• Biochemical Research: Serves as a key intermediate in studies investigating the metabolic activation pathways of polycyclic aromatic hydrocarbons (PAHs) and their role in DNA adduct formation.
• Toxicology & Carcinogenicity Studies: Employed in in vitro and in vivo models to understand the mechanisms of PAH-induced toxicity and cancer.
• Environmental Analysis: Critical for calibrating equipment and validating methods used to monitor PAH pollution and biodegradation products in soil, water, and air samples.
• Enzyme Activity Assays: Used as a specific substrate for studying the activity of dioxygenase and epoxide hydrolase enzymes involved in xenobiotic metabolism.

Basic Information

Product Name	Chrysene-1,2-Dihydrodiol
CAS No.	28622-71-1
Molecular Formula	C₁₈H₁₄O₂
Molecular Weight	262.30 g/mol
Synonyms	1,2-Dihydroxy-1,2-dihydrochrysene; Chrysene 1,2-diol; (+/-)-Chrysene-1,2-dihydrodiol; 1,2-Dihydrochrysene-1,2-diol; trans-Chrysene-1,2-dihydrodiol; Chrysene-1,2-diol (dihydro); Benz[a]phenanthrene-1,2-dihydrodiol; PAH Metabolite Standard
EINECS	Contact for details

Quality Control

Our Chrysene-1,2-Dihydrodiol is manufactured under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, spectroscopic identification (IR, NMR), and confirmation of stereochemistry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This product is light-sensitive (store away from light). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.