Description

6-Bromo-2-Naphthyl-α-D-Mannopyranoside is a specialized glycoside derivative that serves as a critical biochemical tool and synthetic intermediate. Its core value lies in its utility as a chromogenic or fluorogenic substrate for the detection and study of α-mannosidase enzyme activity. This compound is essential for researchers and manufacturers in the life sciences sector, particularly those involved in enzymology, diagnostic assay development, and carbohydrate chemistry research.

Application

• Enzyme Substrate for α-Mannosidase: Primary use as a chromogenic or fluorogenic substrate in enzymatic assays for detecting and quantifying α-mannosidase activity in research and diagnostic applications.
• Biochemical Research Reagent: A key tool for studying enzyme kinetics, inhibition, and the role of glycosidases in biological pathways and disease states.
• Diagnostic Kit Manufacturing: Used in the formulation of diagnostic kits for genetic disorders like α-mannosidosis and for quality control in biopharmaceutical production.
• Carbohydrate Chemistry Synthesis: Serves as a protected glycosyl donor or acceptor in the synthetic elaboration of complex oligosaccharides and glycoconjugates.
• Cell Biology & Histochemistry: Employed in cell-based assays and tissue staining techniques to localize and visualize enzyme activity.
• Pharmaceutical Intermediate: Potential use as a building block in the research and development of glycosidase inhibitor drugs or other therapeutic agents.

Basic Information

Product Name	6-Bromo-2-Naphthyl-α-D-Mannopyranoside
CAS No.	28541-84-6
Molecular Formula	C₁₆H₁₇BrO₆
Molecular Weight	385.21 g/mol
Synonyms	6-Bromo-2-naphthyl α-D-mannopyranoside; 6-Br-2-Naphthyl-α-D-Mannoside; α-D-Mannopyranoside, 6-bromo-2-naphthyl; 2-Naphthol, 6-bromo-, α-D-mannopyranoside; 6-Bromo-2-naphthyl-α-mannoside; Bromonaphthyl Mannopyranoside; α-Mannosidase Substrate (6-Bromo-2-naphthyl); 6-Br-α-Man
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Naphthyl-α-D-Mannopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.