Description

1-O,2-O:3-O,5-o-Diisopropylidene-α-D-Glucofuranose is a protected sugar derivative, a crucial chiral building block in organic synthesis. Its value lies in its ability to mask reactive hydroxyl groups, enabling selective functionalization of the carbohydrate scaffold. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for the synthesis of nucleosides, glycosides, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of antiviral and anticancer nucleoside analogs.
• Chiral Auxiliary/Synthon: Used in asymmetric synthesis to impart stereochemistry in complex molecule construction.
• Glycochemistry Research: Serves as a protected precursor for the preparation of complex oligosaccharides and glycoconjugates.
• Agrochemical Synthesis: Intermediate in the production of certain chiral pesticides and plant growth regulators.
• Fine Chemical Production: Building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: Fundamental reagent in carbohydrate chemistry and medicinal chemistry research programs.

Basic Information

Product Name	1-O,2-O:3-O,5-o-Diisopropylidene-α-D-Glucofuranose
CAS No.	28528-94-1
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:3,5-Di-O-Isopropylidene-α-D-Glucofuranose; Diacetone-D-Glucose; Diacetone Glucose; 1,2:3,5-Di-O-(1-Methylethylidene)-α-D-Glucofuranose; α-D-Glucofuranose, 1,2:3,5-bis-O-(1-methylethylidene)-; Diisopropylidene Glucose; D-(+)-Diacetoneglucose; 1,2-O-Isopropylidene-3,5-O-isopropylidene-α-D-glucofuranose
EINECS	249-090-7

Quality Control

Our 1-O,2-O:3-O,5-o-Diisopropylidene-α-D-Glucofuranose is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-18.5° to -20.5° (c=1 in H2O)
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.